Histopathological diagnostics in endoprosthesis loosening

被引：9

作者：

Morawietz L. ^{[1
,5
]}

Gehrke T. ^{[2
]}

Schröder J.H. ^{[3
]}

Krenn V. ^{[4
]}

机构：

[1] Institut für Pathologie, Charité Universitätsmedizin, Berlin

[2] ENDO-Klinik, Hamburg

[3] Klinik für Orthopädie, Charité Universitätsmedizin, Berlin

[4] Institut für Pathologie, Trier

[5] Institut für Pathologie, Charité Universitätsmedizin, 10117 Berlin

来源：

Der Pathologe | 2006年 / 27卷 / 6期

关键词：

Aseptic loosening; Endoprosthesis; Periprosthetic membrane; Prosthesis loosening; Septic loosening;

D O I：

10.1007/s00292-006-0867-5

中图分类号：

学科分类号：

摘要：

The implantation of total joint endoprostheses has become a routine procedure, being executed about 1.5 million times per year worldwide. The indications are osteoarthritis, rheumatic diseases, trauma and bone neoplasia. However, about 5-12% of patients develop pain and impaired function of the endoprosthesis within 10 years, necessitating revision surgery. During this operation, the so-called periprosthetic membrane between bone and prosthesis is removed. This connective tissue membrane has a pathogenetic impact on the loosening process and can be evaluated by histopathology. This article aims at elucidating the defined histomorphological criteria for the standardized diagnostics of periprosthetic membranes using a recently established classification system. © 2006 Springer Medizin Verlag.

引用

页码：439 / 446

页数：7

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