Effects of low level radiation from the Chernobyl accident in a population with iodine deficiency

被引：0

作者：

E. P. Kasatkina

D. E. Shilin

A. L. Rosenbloom

M. I. Pykov

G. V. Ibragimova

V. N. Sokolovskaya

A. N. Matkovskaya

T. N. Volkova

E. A. Odoud

M. I. Bronshtein

A. M. Poverenny

N. M. Mursankova

机构：

[1] Russian Academy of Advanced Medical Studies,

[2] Department of Pediatric and Adolescent Endocrinology,undefined

[3] 20 Chasovaya Strasse,undefined

[4] Moscow,undefined

[5] 125315,undefined

[6] Russian Federation,undefined

[7] Department of Paediatrics,undefined

[8] University of Florida College of Medicine,undefined

[9] Gainesville,undefined

[10] Florida,undefined

[11] USA,undefined

[12] Children's Medical Services Center,undefined

[13] 1701 SW 16th Avenue,undefined

[14] Gainesville,undefined

[15] Florida 32608,undefined

[16] USA,undefined

来源：

European Journal of Pediatrics | 1997年 / 156卷

关键词：

Key words Radiation; Thyroid; Autoimmunity; Iodine; Chernobyl;

D O I：

暂无

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学科分类号：

摘要：

To determine the effects of low dose radiation from 131I and 137Cs resulting from the Chernobyl disaster on the expression of endemic goiter in children, we studied children in regions with and without evidence of radiocontamination but comparable iodine insufficiency. We included 89 children in the study (radiocontaminated) region (SR) and 116 in the control region (CR) because they were either fetuses, infants, or pre-adolescents at the time of exposure. We evaluated thyroid dimensions by clinical examination and ultrasound; thyroid function by hormonal levels, and thyroglobulin measurement; histology of the thyroid by fine needle aspiration; and thyroid autoimmunity. SR subjects had 5 times the frequency of thyroid enlargement as those from CR, greatest in the younger patients. There were no instances of clinically apparent thyroid dysfunction. Antithyroid microsomal and antithyroglobulin antibodies were present in a markedly greater percentage of SR subjects. Fine needle biopsy demonstrated greater cellular proliferation in samples from SR.

引用

页码：916 / 920

页数：4