Histological evaluation of liver in two rheumatoid arthritis patients with chronic hepatitis B and C treated with TNF-alpha blockade: case reports

被引：0
|
作者：
Primal P. Kaur
Virginia C. Chan
Steven N. Berney
机构：
[1] Temple University School of Medicine,Division of Rheumatology, Department of Medicine
[2] Kaiser Permanente,Imperial/Orchard Medical Offices
来源：
Clinical Rheumatology | 2008年 / 27卷
关键词：
Hepatitis B; Hepatitis C; Rheumatoid arthritis; TNF-alpha blockers;
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暂无
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摘要：
Tumor necrosis factor (TNF)-alpha antagonists successfully modulate the pathogenesis of rheumatoid arthritis (RA). However, little is known about the effect of TNF-alpha blockade on the histology of chronic viral hepatitis. We describe the cases of two patients with RA, one with concurrent chronic hepatitis B virus and the other with hepatitis C virus infection who, as part of their evaluation, underwent liver biopsies while undergoing treatment with a TNF-alpha antagonist.
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