A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models

[1] Burr DB(1998)The importance of subchondral bone in osteoarthrosis Curr Opin Rheumatol 10 256-262

[2] Grynpas MD(1991)Subchondral bone in osteoarthritis Calcif Tissue Int 49 20-26

[3] Alpert B(2003)Changes in articular cartilage and subchondral bone histomorphometry in osteoarthritic knee joints in humans Bone 32 284-290

[4] Katz I(2003)MicroCT evaluation of normal and osteoarthritic bone structure in human knee specimens J Orthop Res 21 6-13

[5] Lieberman I(2007)Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis Osteoarthritis Cartilage 15 179-186

[6] Pritzker KP(1997)Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis Ann Rheum Dis 56 247-254

[7] Bobinac D(2001)A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage J Orthop Res 19 914-918

[8] Spanjol J(2006)Subchondral bone micro-architectural alterations in osteoarthritis: a synchrotron micro-computed tomography study Osteoarthritis Cartilage 14 215-223

[9] Zoricic S(2004)The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K Bone 34 527-538

[10] Maric I(1993)A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months Arthritis Rheum 36 1460-1467

[1] Burr DB(1998)The importance of subchondral bone in osteoarthrosis Curr Opin Rheumatol 10 256-262

[2] Grynpas MD(1991)Subchondral bone in osteoarthritis Calcif Tissue Int 49 20-26

[3] Alpert B(2003)Changes in articular cartilage and subchondral bone histomorphometry in osteoarthritic knee joints in humans Bone 32 284-290

[4] Katz I(2003)MicroCT evaluation of normal and osteoarthritic bone structure in human knee specimens J Orthop Res 21 6-13

[5] Lieberman I(2007)Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis Osteoarthritis Cartilage 15 179-186

[6] Pritzker KP(1997)Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis Ann Rheum Dis 56 247-254

[7] Bobinac D(2001)A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage J Orthop Res 19 914-918

[8] Spanjol J(2006)Subchondral bone micro-architectural alterations in osteoarthritis: a synchrotron micro-computed tomography study Osteoarthritis Cartilage 14 215-223

[9] Zoricic S(2004)The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K Bone 34 527-538

[10] Maric I(1993)A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months Arthritis Rheum 36 1460-1467