A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

被引：0
作者：
Chi Luo
Ji-Hong Lim
Yoonjin Lee
Scott R. Granter
Ajith Thomas
Francisca Vazquez
Hans R. Widlund
Pere Puigserver
机构：
[1] Harvard Medical School,Department of Cancer Biology, Dana
[2] Harvard University,Farber Cancer Institute and Department of Cell Biology
[3] Brigham and Women’s Hospital,Department of Chemistry and Chemical Biology
[4] Harvard Medical School,Department of Pathology
[5] Broad Institute of Harvard and MIT,Department of Medical Oncology
[6] Dana-Farber Cancer Institute,Department of Dermatology
[7] Harvard Medical School,undefined
[8] Brigham and Women’s Hospital,undefined
[9] Harvard Medical School,undefined
[10] †Present address: Department of Biomedical Chemistry,undefined
[11] College of Biomedical and Health Science,undefined
[12] Konkuk University,undefined
[13] Chungbuk,undefined
[14] Chungju,undefined
[15] Chungcheongbuk-do 380-701,undefined
[16] South Korea.,undefined
来源：
Nature | 2016年 / 537卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
PGC1α suppresses melanoma metastasis and promotes growth and survival in primary tumours, whilst inhibition of PGC1α induces increased invasion and metastasis.
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页码：422 / 426
页数：4
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