Rare subclonal sequencing of breast cancers indicates putative metastatic driver mutations are predominately acquired after dissemination

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作者
Matthew R. Lawrence-Paul
Tien-chi Pan
Dhruv K. Pant
Natalie N. C. Shih
Yan Chen
George K. Belka
Michael Feldman
Angela DeMichele
Lewis A. Chodosh
机构
[1] 2-PREVENT Translational Center of Excellence,Department of Cancer Biology
[2] Abramson Family Cancer Research Institute,Department of Pathology & Laboratory Medicine
[3] Perelman School of Medicine at the University of Pennsylvania,Department of Medicine
[4] Perelman School of Medicine at the University of Pennsylvania,Department of Biostatistics, Epidemiology and Informatics
[5] Perelman School of Medicine at the University of Pennsylvania,undefined
[6] Perelman School of Medicine at the University of Pennsylvania,undefined
来源
Genome Medicine | / 16卷
关键词
Breast cancer; Metastasis; Rare subclonal sequencing; Ultra-deep sequencing; Genomics; Metastatic driver mutation;
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