The expression of TNF-α and ICAM-1 in lesions of lichen planus and its implication

被引：0
|
作者：
Xu’e Chen
Zhixiang Liu
Qing Yue
Houjun Liu
Yan Wu
Jiawen Li
机构：
[1] Huazhong University of Science Technology,Department of Dermatology, Union Hospital, Tongji Medical College
来源：
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2007年 / 27卷
关键词：
TNF-α; ICAM-1; lichen planus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In order to investigate the role of TNF-and ICAM-1 in the pathogenesis of lichen planus, immunohistochemistry was used to detect the expression of TNF-and ICAM-1 in skin lesions of the patients with lichen planus and skin tissues of normal subjects. The results showed that positive rates of TNF-α and ICAM-1 expressions in lichen planus were significantly higher than those in normal skins (both P<0.05). Meanwhile, there was a obvious correlation between the increase of TNF-α and that of ICAM-1 in lichen planus. The expression of TNF-α and ICAM-1 might play an important role in the development of lichen planus.
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页码：739 / 741
页数：2
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