Rad51-mediated double-strand break repair and mismatch correction of divergent substrates

被引：0

作者：

Ranjith Anand

Annette Beach

Kevin Li

James Haber

机构：

[1] Brandeis University,Rosenstiel Basic Medical Sciences Research Center and Department of Biology

[2] †Present address: Ginkgo Bioworks,undefined

[3] Boston,undefined

[4] Massachusetts 02210,undefined

[5] USA.,undefined

来源：

Nature | 2017年 / 544卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

DNA repair by break-induced replication begins with the Rad51-mediated invasion of single-stranded DNA into a double-stranded donor template; this study shows that successful recombination between highly mismatched substrates can occur when only five consecutive bases can be paired and that mismatch correction is most efficient near the invading end of the recipient strand.

引用

页码：377 / 380

页数：3

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