Human bone marrow-derived mesenchymal stromal cells cultured in serum-free media demonstrate enhanced antifibrotic abilities via prolonged survival and robust regulatory T cell induction in murine bleomycin-induced pulmonary fibrosis

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作者
Shun Takao
Taku Nakashima
Takeshi Masuda
Masashi Namba
Shinjiro Sakamoto
Kakuhiro Yamaguchi
Yasushi Horimasu
Shintaro Miyamoto
Hiroshi Iwamoto
Kazunori Fujitaka
Hironobu Hamada
Shinya Takahashi
Ayumu Nakashima
Noboru Hattori
机构
[1] Hiroshima University,Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences
[2] Hiroshima University Hospital,Department of Clinical Oncology
[3] Hiroshima University,Department of Physical Analysis and Therapeutic Sciences, Graduate School of Biomedical and Health Sciences
[4] Hiroshima University,Department of Cardiovascular Surgery, Graduate School of Medicine
[5] Hiroshima University,Department of Stem Cell Biology and Medicine, Graduate School of Biomedical and Health Sciences
来源
Stem Cell Research & Therapy | / 12卷
关键词
Mesenchymal stromal cells; Serum-free; Bleomycin; Pulmonary fibrosis; Regulatory T cells; Interleukin-6; Transforming growth factor-β;
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