Effect of a Polymorphonuclear Elastase Inhibitor (Sivelestat Sodium) on Acute Lung Injury After Cardiopulmonary Bypass: Findings of a Double-Blind Randomized Study

被引:0
作者
Masahiro Ryugo
Yoshiki Sawa
Hiroshi Takano
Goro Matsumiya
Shigemitsu Iwai
Masamichi Ono
Hiroki Hata
Takashi Yamauchi
Masaji Nishimura
Yuji Fujino
Hikaru Matsuda
机构
[1] Osaka University Graduate School of Medicine,Division of Cardiovascular Surgery, Department of Surgery
[2] Osaka University Hospital,Intensive Care Unit
来源
Surgery Today | 2006年 / 36卷
关键词
Polymorphonuclear elastase; Sivelestat sodium; Acute lung injury; Systemic inflammatory response syndrome; Cardiopulmonary bypass; Postperfusion syndrome;
D O I
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页码:321 / 326
页数:5
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[1]  
Yamazaki T(1999)Protective effects of ONO-5046*Na, a specific neutrophil elastase inhibitor, on postperfusion lung injury Ann Thorac Surg 68 2141-6
[2]  
Ooshima H(1992)Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 20 864-74
[3]  
Usui A(1994)The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination Am J Respir Crit Care Med 149 818-24
[4]  
Watanabe T(1993)Elevation of cytokines during open heart surgery with cardiopulmonary bypass: participation of interleukin 8 and 6 in reperfusion injury Can J Anaesth 40 1016-21
[5]  
Yasuura K(1997)Effect of cardiopulmonary bypass under tepid temperature on inflammatory reaction Ann Thorac Surg 64 124-8
[6]  
Bernard GR(1994)Circulating cytokines in patients undergoing normothermic cardiopulmonary bypass J Thorac Cardiovasc Surg 108 636-41
[7]  
Artigas A(1996)Human cytokine responses to cardiac transplantation and coronary artery bypass grafting J Thorac Cardiovasc Surg 111 469-77
[8]  
Brigham KL(1996)Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations J Thorac Cardiovasc Surg 111 29-35
[9]  
Carlet J(1993)Organ dysfunction and cardiopulmonary bypass: the role of complement and complement regulatory proteins Eur J Cardiothorac Surg 7 563-73
[10]  
Falke K(1983)Complement and the damaging effects of cardiopulmonary bypass J Thorac Cardiovasc Surg 86 845-57