Role of Ca2+ and transmitters of the sympathetic nervous system in transduction of stress signal in cardiomyocytes

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作者
I. V. Shemarova
V. P. Nesterov
机构
[1] Russian Academy of Sciences,Sechenov Institute of Evolutionary Physiology and Biochemistry
关键词
Nervous System; Protein Kinase; Sympathetic Nervous System; Stress Signal; Current Concept;
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摘要
This review summarizes current concepts of the role of Ca2+ and neurotransmitters of the sympathetic nervous system in transduction of stress signals leading to apoptosis or cell hypertrophy of cardiomyocytes. A particular attention is paid to consideration of contribution of MAP-kinases (mitogen-activated protein kinases) to transduction of stress signals coming into cardiomyocytes through mechanism of interaction of adrenoreceptors with ligands.
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页码:117 / 127
页数:10
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