Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies

被引：0
作者：
Yalan Chen
Xibin Wang
Yuwei Ye
Qian Ren
机构：
[1] Lanzhou University,The First School of Clinical Medicine
[2] The First Hospital of Lanzhou University,Department of Gastroenterology
[3] Lanzhou University,Gansu Province Clinical Research Center for Digestive Diseases
来源：
Medical Oncology | / 41卷
关键词：
Gut microbiota; Metabolites; Cancer; Probiotics; Fecal microbiota transplantation; Chemotherapy; Radiotherapy; Immunotherapy;
D O I：
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学科分类号：
摘要：
In recent years, the role of gut microbiota in cancer treatment has attracted substantial attention. It is now well established that gut microbiota and its metabolites significantly contribute to the incidence, treatment, and prognosis of various cancers. This review provides a comprehensive review on the pivotal role of gut microbiota and their metabolites in cancer initiation and progression. Furthermore, it evaluates the impact of gut microbiota on the efficacy and associated side effects of anticancer therapies, including radiotherapy, chemotherapy, and immunotherapy, thus emphasizing the clinical importance of gut microbiota reconstitution in cancer treatment.
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