Safety and immunogenicity of a freeze-dried, Vero cell culture-derived, inactivated Japanese encephalitis vaccine (KD-287, ENCEVAC®) versus a mouse brain-derived inactivated Japanese encephalitis vaccine in children: a phase III, multicenter, double-blinded, randomized trial

被引：0

作者：

Ki Wook Yun

Hoan Jong Lee

Jin Han Kang

Byung Wook Eun

Yae-Jean Kim

Kyung-Hyo Kim

Nam Hee Kim

Young Jin Hong

Dong Ho Kim

Hwang Min Kim

Sung-Ho Cha

机构：

[1] Seoul National University College of Medicine,Department of Pediatrics

[2] Chung-Ang University College of Medicine,Department of Pediatrics

[3] The Catholic University of Korea,Department of Pediatrics, College of Medicine

[4] Eulji University School of Medicine,Department of Pediatrics, Eulji General Hospital

[5] Sungkyunkwan University School of Medicine,Departments of Pediatrics, Samsung Medical Center

[6] Ewha Womans University,Department of Pediatrics, School of Medicine

[7] Inje University College of Medicine,Department of Pediatrics, Ilsan Paik Hospital

[8] Inha University College of Medicine,Department of Pediatrics

[9] Korea Cancer Center Hospital,Department of Pediatrics

[10] Yonsei University Wonju College of Medicine,Department of Pediatrics

[11] Kyunghee University,Department of Pediatrics, College of Medicine

来源：

BMC Infectious Diseases | / 15卷

关键词：

Japanese encephalitis; Vaccine; Vero cells; Clinical trial;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 128 条

[1] Solomon T(2004)Flavivirus encephalitis N Engl J Med 351 370-8
[2] Solomon T(2006)Control of Japanese encephalitis–within our grasp? N Engl J Med 355 869-71
[3] Yang SE(2006)The efficacy of mouse-brain inactivated Nakayama strain Japanese encephalitis vaccine–results from 30 years experience in Taiwan Vaccine 24 2669-73
[4] Pan MJ(2011)New Japanese encephalitis vaccines: alternatives to production in mouse brain Expert Rev Vaccines 10 355-64
[5] Tseng HF(2011)Safety profile of the Vero cell-derived Japanese encephalitis virus (JEV) vaccine IXIARO((R)) Vaccine 29 8669-76
[6] Liau MY(2012)The history of vaccination and current vaccination policies in Korea Clin Exp Vaccine Res 1 3-8
[7] Halstead SB(2007)Safety and immunogenicity of a Vero-cell-derived, inactivated Japanese encephalitis vaccine: a non-inferiority, phase III, randomised controlled trial Lancet 370 1847-53
[8] Thomas SJ(2008)Randomized, double-blind, placebo-controlled phase 3 trial of the safety and tolerability of IC51, an inactivated Japanese encephalitis vaccine J Infect Dis 198 493-299
[9] Schuller E(2012)Superior immunogenicity of a freeze-dried, cell culture-derived Japanese encephalitis vaccine (inactivated) Vaccine 30 2329-35
[10] Klingler A(2010)Immunogenicity and safety of IXIARO (IC51) in a Phase II study in healthy Indian children between 1 and 3 years of age Vaccine 28 834-9