Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

被引:0
作者
Ansgar Brüning
Klaus Friese
Alexander Burges
Ioannis Mylonas
机构
[1] Ludwig-Maximilians-University Munich,Department of Obstetrics and Gynaecology, Campus Innenstadt
[2] Ludwig-Maximilians-University Munich,Department of Obstetrics and Gynaecology, Campus Grosshadern
来源
Breast Cancer Research | / 12卷
关键词
Breast Cancer Cell; Tamoxifen; MCF7 Cell; Endoplasmic Reticulum Stress; Breast Cancer Cell Line;
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[1]  
Jemal A(2009)Cancer statistics, 2009 CA Cancer J Clin 59 225-249
[2]  
Siegel R(2009)Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009 Ann Oncol 20 1319-1329
[3]  
Ward E(1992)Systemic therapy in node-negative patients: updated findings from NSABP clinical trials. National Surgical Adjuvant Breast and Bowel Project J Natl Cancer Inst Monogr 11 105-116
[4]  
Hao Y(2008)The endocrine prevention of breast cancer Best Pract Res Clin Endocrinol Metab 22 615-623
[5]  
Xu J(2009)Endocrine therapy for the treatment of postmenopausal women with breast cancer Expert Rev Anticancer Ther 9 187-198
[6]  
Thun MJ(1996)Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells J Biol Chem 271 13504-13514
[7]  
Goldhirsch A(2001)Mechanisms of tamoxifen-induced apoptosis Apoptosis 6 469-477
[8]  
Ingle JN(2006)HIV protease inhibitors decrease VEGF/HIF-1α expression and angiogenesis in glioblastoma cells Neoplasia 8 889-895
[9]  
Gelber RD(2007)Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo Clin Cancer Res 13 5183-5194
[10]  
Coates AS(2007)Biomedicine. HIV drug shows promise as potential cancer treatment Science 317 1305-635