Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC)

被引:0
作者
Mark Clemons
Sasha Mazzarello
John Hilton
Anil Joy
Julie Price-Hiller
Xiaofu Zhu
Shailendra Verma
Anne Kehoe
Mohammed FK Ibrahim
Marta Sienkiewicz
Carol Stober
Lisa Vandermeer
Brian Hutton
Ranjeeta Mallick
Dean Fergusson
机构
[1] The University of Ottawa,Department of Medicine, Division of Medical Oncology, The Ottawa Hospital Cancer Centre
[2] The Ottawa Hospital Research Institute,Cancer Research Program
[3] The Ottawa Hospital Research Institute,Clinical Epidemiology Program
[4] Cross Cancer Institute,Division of Medical Oncology, Department of Oncology, University of Alberta
来源
Supportive Care in Cancer | 2019年 / 27卷
关键词
Integrated consent model; Breast cancer; Febrile neutropenia; Filgrastim; Ciprofloxacin;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1345 / 1354
页数:9
相关论文
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[11]  
Sandbach J(2014)Informed consent for pragmatic trials--the integrated consent model N Engl J Med 370 769-772
[12]  
Hyman WJ(2014)Ethics and regulatory complexities for pragmatic clinical trials JAMA 311 2381-2382
[13]  
Khandelwal P(2010)Management of febrile neutropenia: ESMO clinical practice guidelines Ann Oncol : official journal of the European Society for Medical Oncology 21 v252-v256
[14]  
Negron AG(2009)Docetaxel with cyclophosphamide is associated with an overall survival benefit compared with doxorubicin and cyclophosphamide: 7-year follow-up of US oncology research trial 9735 J Clin Oncol 27 1177-1183
[15]  
Richards DA(2011)Are patients in clinical trials representative of the general population? Dose intensity and toxicities associated with FE100C-D chemotherapy in a non-trial population of node positive breast cancer patients compared with PACS-01 trial group Eur J Cancer 47 215-220
[16]  
Anthony SP(2011)Real-world experience with adjuvant fec-d chemotherapy in four Ontario regional cancer centres Curr Oncol 18 119-125
[17]  
Mennel RG(2010)Febrile neutropenia rates with adjuvant docetaxel and cyclophosphamide chemotherapy in early breast cancer: discrepancy between published reports and community practice-a retrospective analysis Curr Oncol 17 2-3
[18]  
Boehm KA(2009)High rate of febrile neutropenia in patients with operable breast cancer receiving docetaxel and cyclophosphamide J Clin Oncol 27 e101-e102
[19]  
Meyer WG(2014)Risk and consequences of chemotherapy-induced neutropenic complications in patients receiving daily filgrastim: the importance of duration of prophylaxis BMC Health Serv Res 14 189-e279
[20]  
Asmar L(2016)Can the referring surgeon enhance accrual of breast cancer patients to medical and radiation oncology trials? The ENHANCE study Curr Oncol 23 e276-925