Long-standing insulinoma: two case reports and review of the literature Case Reports

被引:8
作者
Tarchouli M. [1 ]
Ait Ali A. [1 ]
Ratbi M.B. [1 ]
Belhamidi M.S. [1 ]
Essarghini M. [1 ]
Aboulfeth E.M. [1 ]
Bouzroud M. [1 ]
Sbitti Y. [2 ]
Oukabli M. [3 ]
Elfahssi M. [1 ]
Sair K. [1 ]
机构
[1] Department of Digestive Surgery, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat
[2] Department of Oncology, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat
[3] Department of Pathology, Faculty of Medicine and Pharmacy, Mohammed V Military Hospital, Mohammed V University, Rabat
关键词
Diagnosis; Insulinoma; Management; Pancreas; Surgery;
D O I
10.1186/s13104-015-1424-1
中图分类号
学科分类号
摘要
Background: Insulinomas are rare pancreatic endocrine tumors. Most are benign and solitary. However, the nonspecific symptoms and small size of these tumors led to difficulties of diagnosis and localization. Case presentation: We present two Arab patients with pancreatic long-standing insulinoma. Both patients presented episodic hypoglycemic symptoms respectively during 10 and 2 years. Biochemical and morphological workup detected localized pancreatic insulinoma. Open procedure surgery was done for the two patients and insulinomas were successfully removed by enucleation. Conclusion: Insulinoma remains a diagnostic challenge to practitioners. Diagnosis of suspected cases is easily confirmed by standard endocrine tests, especially the supervised fasting test. Accurate preoperative localization is essential for more effective and safest surgery. © 2015 Tarchouli et al.
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页码:1 / 6
页数:5
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[21]  
Klimstra D.S., Modlin I.R., Coppola D., Lloyd R.V., Suster S., The pathologic classification of neuroendocrine tumors: a review of nomenclature, grading, and staging systems, Pancreas, 39, pp. 707-712, (2010)