Nuclease activity of 2-substituted heteroaromatic thiosemicarbazone and semicarbazone copper(II) complexes

被引：2
作者：
Hussain Reddy K. [1 ]
Sambasiva Reddy P. [1 ]
Ravindra Babu P. [1 ,2 ]
机构：
[1] Department of Chemistry, Sri Krishnadevaraya University
[2] School of Life Sciences, University of Hyderabad
来源：
Transition Metal Chemistry | 2000年 / 25卷 / 02期
关键词：
Ketone; Schiff Base; Schiff; Electrochemical Reduction; Base Complex;
D O I：
10.1023/A:1007027011216
中图分类号：
学科分类号：
摘要：
Copper(II) Schiff base complexes derived from furan-2-carboxaldehyde, 2-furylmethyl ketone, thiophene-2-carboxaldehyde and methyl-2-thienyl ketone with semicarbazide and thiosemicarbazide have been prepared and characterized by analytical, i.r., electronic, e.s.r. and c.v. spectral data. The electronic spectral d-d band position varies from 744-415 nm in pyridine and 872-371 nm in DMF. E.s.r. g∥ values lie between 2.1439 and 2.3149 at LNT. All complexes undergo quasi-reversible one-electron electrochemical reduction (CuIII/CuII) in the 0.42-0.52 V potential range. The electron transfer is much faster in thiosemicarbazone complexes compared to semicarbazone complexes. All these copper(II) complexes showed increased nuclease activity in presence of oxidant.
引用
收藏
页码：154 / 160
页数：6
相关论文
共 41 条
[1]  
Padhye S., Coord. Chem. Rev., 63, (1985)
[2]  
Perrin D.D., Stunzi H., Pharm. Therm., 12, (1985)
[3]  
Campbell M.J.M., Coord. Chem. Rev., 15, (1975)
[4]  
Oxford J.S., Perrin D.D., Gen. Virol., 23, (1974)
[5]  
Ranganathan D., Patel B.K., Mishra R.K., J. Chem. Soc., Chem. Commun., (1994)
[6]  
Magada D., Miller R.A., Sessler J.L., Iverson B., J. Am. Chem. Soc., 116, (1994)
[7]  
Matsumura K., Endo M., Komiyama M., J. Chem. Soc. Chem. Commun., (1994)
[8]  
Sigman D.S., Bruice T.W., Mazumder A., Sutton C.L., Acc. Chem. Res., 26, (1993)
[9]  
Meunier B., Chem. Rev., 92, (1992)
[10]  
Pyle A.M., Barton J.K., Inorg. Chem., 38, (1990)
12345