MR imaging of the contralateral breast in patients after breast-conserving therapy

被引：34

作者：

Viehweg P. ^{[1
]}

Rotter K. ^{[2
]}

Laniado M. ^{[1
]}

Lampe D. ^{[3
]}

Buchmann J. ^{[4
]}

Kölbl H. ^{[3
]}

Heywang-Köbrunner S. ^{[2
]}

机构：

[1] Institute of Diagnostic Radiology, Technical University Dresden, 01307 Dresden

[2] Department of Diagnostic Radiology, Martin Luther Univ. Halle Wittenberg, 06097 Halle

[3] Department of Gynaecology, Martin Luther Univ. Halle Wittenberg, 06097 Halle

[4] Institute of Pathology, Martin Luther Univ. Halle Wittenberg, 06097 Halle

来源：

European Radiology | 2004年 / 14卷 / 3期

关键词：

Breast; Breast neoplasms; Diagnosis; MR imaging;

D O I：

10.1007/s00330-003-2086-2

中图分类号：

学科分类号：

摘要：

A study was undertaken to assess the diagnostic accuracy of contrast-enhanced MR mammography (MRM) of the contralateral breast in patients treated by breast-conserving therapy previously. A total of 119 patients underwent 145 standardized dynamic MR studies (1 T, T1-weighted 3D FLASH, 0.2 mmol Gd-DTPA/kg body weight). We retrospectively evaluated the results of conventional methods and MRM. A total of 11 contralateral carcinomas were present (detection rate 9%). The interval between treatment of the first primary and identification of contralateral malignancy was 9-80 months (mean 33 months). The MRM allowed detection of four otherwise occult malignancies. One of 11 cancer was missed on MRM due to benign appearance of enhancement. Compared with conventional methods MRM improved sensitivity (91 vs 64%) and specificity (90 vs 84%), respectively. This study suggests that additional MRM of the contralateral breast increases the diagnostic accuracy not only by enhancing the detection of second cancers but also by reducing false-positive results. © Springer-Verlag 2003.

引用

页码：402 / 408

页数：6

共 18 条

[1]

Chen Y., Thompson W., Semenciw R., Et al., Epidemiology of contralateral breast cancer, Cancer Epidemiol. Biomarkers Prev., 8, pp. 855-861, (1999)

[2]

Roubidoux M.A., Helvie M.A., Lai N., Et al., Bilateral breast cancer: Early detection with mammography, Radiology, 196, pp. 427-431, (1995)

[3]

Recommended breast cancer surveillance guidelines, J. Clin. Oncol., 15, pp. 2149-2156, (1997)

[4]

Harms S.E., Flamig D.P., Hesley K.L., Et al., MR imaging of the breast with rotating delivery excitation off resonance: Clinical experience with pathologic correlation, Radiology, 197, pp. 493-501, (1993)

[5]

Orel S.G., Schnall M.D., Powell C.M., Et al., Staging of suspected breast cancer: Effect of MR imaging and MR-guided biopsy, Radiology, 196, pp. 115-122, (1995)

[6]

Heywang-Kobrunner S.H., Viehweg P., Heinig A., Et al., Contrast-enhanced MRI of the breast: Accuracy, value, controversies, solutions, Eur. J. Radiol., 24, pp. 94-108, (1997)

[7]

Rieber A., Brahms H.J., Gabelmann A., Et al., Breast MRI for monitoring response of primary breast cancer to neo-adjuvant chemotherapy, Eur. Radiol., 12, pp. 1711-1719, (2002)

[8]

Fischer U., Vosshenrich R., Probst A., Et al., Preoperative MR mammography in patients with breast cancer: Useful information or useless extravagance?, Fortschr. Geb. Rontgenstr. Neuen. Bildgeb. Verfahr., 161, 4, pp. 300-306, (1994)

[9]

Rieber A., Merkle E., Bohm W., Et al., MRI of histologically confirmed mammary carcinoma: Clinical relevance of diagnostic procedures for detection of multifocal or contralateral secondary carcinoma, J. Comput. Assist. Tomogr., 21, pp. 773-779, (1997)

[10]

Liberman L., Morris E.A., Kim C.M., Et al., MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer, AJR, 180, pp. 333-341, (2003)

← 1 2 →