Common use of dietary supplements for bipolar disorder: a naturalistic, self-reported study

被引：10

作者：

Bauer M. ^{[1
]}

Glenn T. ^{[2
]}

Conell J. ^{[1
]}

Rasgon N. ^{[3
]}

Marsh W. ^{[4
]}

Sagduyu K. ^{[5
]}

Munoz R. ^{[6
]}

Lewitzka U. ^{[1
]}

Bauer R. ^{[1
]}

Pilhatsch M. ^{[1
]}

Monteith S. ^{[7
]}

Whybrow P.C. ^{[8
]}

机构：

[1] Department of Psychiatry and Psychotherapy, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden

[2] ChronoRecord Association Inc., Fullerton, 92834, CA

[3] Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Palo Alto, 94305-5723, CA

[4] Department of Psychiatry, University of Massachusetts, Worcester, 01655, MA

[5] Department of Psychiatry, University of Missouri Kansas City School of Medicine, Stanley, P.O. Box 23430, Kansas City, 66283, KS

[6] Department of Psychiatry, University of California San Diego, San Diego, CA

[7] Michigan State University College of Human Medicine, Traverse City Campus, Traverse City, MI

[8] Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior University of California Los Angeles (UCLA), Los Angeles, 90095, CA

来源：

International Journal of Bipolar Disorders | / 3卷 / 1期

关键词：

Melatonin; Bipolar Disorder; Dietary Supplement; Prescription Drug; Mood Stabilizer;

D O I：

10.1186/s40345-015-0029-x

中图分类号：

学科分类号：

摘要：

Background: Dietary supplements are taken by about half of Americans. Knowledge of dietary supplement use is important because they may interact with prescription drugs or other supplements, cause adverse reactions including psychiatric symptoms, or contain inherently toxic ingredients or contaminants. This study explores the use of dietary supplements by patients with bipolar disorder in the US. Methods: Data were obtained from an ongoing, naturalistic study of patients with bipolar disorder who received pharmacological treatment as usual. The patients self-reported their daily mood, sleep, and medications taken, including all drugs prescribed for bipolar disorder or that the patient felt impacted their mood. These included other prescribed drugs, over-the-counter drugs and dietary supplements. Drugs that received premarketing approval from the FDA were not included as dietary supplements. Patient demographics and daily medication use were characterized. Results: Data were available from 348 patients in the US who returned a mean 249.5 days of data. In addition to prescribed psychiatric drugs, 101 of the 348 patients (29 %) used a dietary supplement for at least 7 days and 69 (20 %) used a supplement long term (for at least 50 % of days). Of the 101 supplement users, 72 (71.3 %) took one supplement daily. The 101 patients tried over 40 different supplements, and the long-term users took 19 different supplements. The most commonly taken supplements for both groups were fish oil, B vitamins, melatonin, and multivitamins. Patients using supplements were more likely to be white (p < 0.001), older (p = 0.009), and ill for more years (p = 0.025). Conclusions: Many patients with bipolar disorder use dietary supplements in addition to prescribed drugs. Physicians should obtain detailed information about all dietary supplements taken by patients with bipolar disorder. © 2015, Bauer et al.; licensee Springer.

引用

页数：7

共 71 条

[1]

Albright C.L., Schembre S.M., Steffen A.D., Wilkens L.R., Monroe K.R., Yonemori K.M., Et al., Differences by race/ethnicity in older adults’ beliefs about the relative importance of dietary supplements vs prescription medications: results from the SURE study, J Acad Nutr Diet, 112, pp. 1223-1229, (2012)

[2]

Andreescu C., Mulsant B.H., Emanuel J.E., Complementary and alternative medicine in the treatment of bipolar disorder—a review of the evidence, J Affect Disord, 110, pp. 16-26, (2008)

[3]

Ashar B.H., Miller R.G., Pichard C.P., Levine R., Wright S.M., Patients’ understanding of the regulation of dietary supplements, J Community Health, 33, pp. 22-30, (2008)

[4]

Bailey R.L., Gahche J.J., Lentino C.V., Dwyer J.T., Engel J.S., Thomas P.R., Et al., Dietary supplement use in the United States: 2003–2006, J Nutr, 141, pp. 261-266, (2011)

[5]

Bailey R.L., Gahche J.J., Miller P.E., Thomas P.R., Dwyer J.T., Why US adults use dietary supplements, JAMA Intern Med, 173, pp. 355-361, (2013)

[6]

Bartholow M., Pharmacy Times, Top 200 drugs of, (2012)

[7]

Bauer M., Grof P., Gyulai L., Rasgon N., Glenn T., Whybrow P.C., Using technology to improve longitudinal studies: self-reporting with chronorecord in bipolar disorder, Bipolar Disord, 6, pp. 67-74, (2004)

[8]

Bauer M., Wilson T., Neuhaus K., Sasse J., Pfennig A., Lewitzka U., Et al., Self-reporting software for bipolar disorder: validation of ChronoRecord by patients with mania, Psychiatry Res, 159, pp. 359-366, (2008)

[9]

Bauer M., Glenn T., Grof P., Rasgon N.L., Marsh W., Sagduyu K., Et al., Frequency of subsyndromal symptoms and employment status in patients with bipolar disorder, Soc Psychiatry Psychiatr Epidemiol, 44, pp. 515-522, (2009)

[10]

Bauer M., Glenn T., Keil M., Bauer R., Marsh W., Grof P., Et al., Brief depressive symptoms in patients with bipolar disorder: analysis of long-term self-reported data, Aust N Z J Psychiatry, 46, pp. 1068-1078, (2012)

← 1 2 3 4 5 6 7 8 →