Cyclic Amidoalkylation of Hydrophosphorylic Compounds. Synthesis of Proline Analogs

被引:0
|
作者
A. V. Vinyukov
M. E. Dmitriev
A. N. Yarkevich
V. V. Ragulin
机构
[1] Russian Academy of Sciences,Institute of Physiologically Active Substances
来源
Russian Journal of General Chemistry | 2017年 / 87卷
关键词
phosphorylic analogs of proline; cyclic amidoalkylation; 4-aminobutyraldehyde;
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摘要
A method for the synthesis of N-Cbz-protected phosphorylic analogs of proline by cyclic amidoalkylation of various hydrophosphorylic compounds was developed. Combination of amide and carbonyl fragments in the 4-N-Cbz-aminobutyraldehyde molecule allows to realize the three-center two-component amide version of the Kabachnik–Fields reaction.
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页码:2898 / 2901
页数:3
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  • [1] Cyclic Amidoalkylation of Hydrophosphorylic Compounds. Synthesis of Proline Analogs
    Vinyukov, A. V.
    Dmitriev, M. E.
    Yarkevich, A. N.
    Ragulin, V. V.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (12) : 2898 - 2901