Pathophysiology of obesity hypertension

被引：119
作者：
Hall J.E. [1 ]
机构：
[1] Department of Physiology and Biophysics, University of Mississippi, Medical Center, Jackson, MS 39216-4505
来源：
Current Hypertension Reports | 2000年 / 2卷 / 2期
关键词：
Brown Adipose Tissue; Sympathetic Activity; Sodium Reabsorption; Obese Person; Excess Weight Gain;
D O I：
10.1007/s11906-000-0073-4
中图分类号：
学科分类号：
摘要：
Excess weight gain is a major cause of essential hypertension, and abnormal kidney function appears to be a cause as well as a consequence of obesity hypertension. Excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role in mediating increased blood pressure associated with weight gain. Activation of the renin-angiotensin and sympathetic nervous systems and physical compression of the kidneys appear to contribute to obesity-induced increases in sodium reabsorption and hypertension. Copyright © 2000 by Current Science Inc.
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收藏
页码：139 / 147
页数：8
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