Contamination of sulfonamide antibiotics and sulfamethazine-resistant bacteria in the downstream and estuarine areas of Jiulong River in Southeast China

被引:0
作者
Danyun Ou
Bin Chen
Renao Bai
Puqing Song
Heshan Lin
机构
[1] State Oceanic Administration,Third Institute of Oceanography
来源
Environmental Science and Pollution Research | 2015年 / 22卷
关键词
Sulfonamides; Sulfamethazine-resistant bacteria; Bacterial diversity; Drug resistance; Surface water; Southeast China;
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中图分类号
学科分类号
摘要
Surface water samples from downstream and estuarine areas of Jiulong River were collected in August 2011 and May 2012 for detecting sulfonamide antibiotic residues and isolating sulfamethazine-resistant bacteria. Sulfamethazine was detected in all samples in May 2012 at an average concentration of 78.3 ng L−1, which was the highest among the nine sulfonamide antibiotics determined. Sulfamethazine-resistant bacteria (SRB) were screened using antibiotic-containing agar plates. The SRB average abundance in the samples was 3.69 × 104 and 2.17 × 103 CFUs mL−1 in August 2011 and May 2012, respectively, and was positively correlated to sulfamethazine concentration in May 2012. The 16S rRNA gene sequencing of all the 121 SRB isolates revealed high diversity. Furthermore, the SRB isolates exhibited multidrug resistance, with 48.7 % showing resistance to at least three antibiotics. The abundance and persistence of highly diverse SRB and their multidrug resistance are likely to demonstrate the transferable pressure from coastal environments on public health.
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页码:12104 / 12113
页数:9
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  • [41] Bååth E(2013)Antimicrobial resistance spread in aquatic environments J Environ Biol 34 345-1685
  • [42] Greve G(2011)Occurrence and risks of antibiotics in the Laizhou Bay, China: impacts of river discharge Chemosphere 84 1677-33
  • [43] Wouterse M(2012)Antibiotics in the offshore waters of the Bohai Sea and the Yellow Sea in China: occurrence, distribution and ecological risks Mar Environ Res 78 26-3440
  • [44] Schmitt H(2013)Occurrence and variations of five classes of antibiotic resistance genes along the Jiulong River in southeast China Proc Natl Acad Sci 110 3435-2920
  • [45] Ding C(2011)Antibiotics pollution in Jiulong River estuary: source, distribution and bacterial resistance Environ Pollut 159 2913-undefined
  • [46] He J(undefined)Occurrence and distribution of antibiotics in the Beibu Gulf, China: impacts of river discharge and aquaculture activities undefined undefined undefined-undefined
  • [47] Enne VI(undefined)Diverse and abundant antibiotic resistance genes in Chinese swine farms undefined undefined undefined-undefined
  • [48] Livermore DM(undefined)Occurrence and distribution of antibiotics in coastal water of the Bohai Bay, China: impacts of river discharge and aquaculture activities undefined undefined undefined-undefined
  • [49] Stephens P(undefined)undefined undefined undefined undefined-undefined
  • [50] Hall LMC(undefined)undefined undefined undefined undefined-undefined