Contamination of sulfonamide antibiotics and sulfamethazine-resistant bacteria in the downstream and estuarine areas of Jiulong River in Southeast China

被引：0
作者：
Danyun Ou
Bin Chen
Renao Bai
Puqing Song
Heshan Lin
机构：
[1] State Oceanic Administration,Third Institute of Oceanography
来源：
Environmental Science and Pollution Research | 2015年 / 22卷
关键词：
Sulfonamides; Sulfamethazine-resistant bacteria; Bacterial diversity; Drug resistance; Surface water; Southeast China;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Surface water samples from downstream and estuarine areas of Jiulong River were collected in August 2011 and May 2012 for detecting sulfonamide antibiotic residues and isolating sulfamethazine-resistant bacteria. Sulfamethazine was detected in all samples in May 2012 at an average concentration of 78.3 ng L−1, which was the highest among the nine sulfonamide antibiotics determined. Sulfamethazine-resistant bacteria (SRB) were screened using antibiotic-containing agar plates. The SRB average abundance in the samples was 3.69 × 104 and 2.17 × 103 CFUs mL−1 in August 2011 and May 2012, respectively, and was positively correlated to sulfamethazine concentration in May 2012. The 16S rRNA gene sequencing of all the 121 SRB isolates revealed high diversity. Furthermore, the SRB isolates exhibited multidrug resistance, with 48.7 % showing resistance to at least three antibiotics. The abundance and persistence of highly diverse SRB and their multidrug resistance are likely to demonstrate the transferable pressure from coastal environments on public health.
引用
收藏
页码：12104 / 12113
页数：9
相关论文
共 255 条
  • [1] Antunes P(2005)Dissemination of sulfonamide resistance genes (sul1, sul2, and sul3) in Portuguese Antimicrob Agents Chemother 49 836-839
  • [2] Machado J(2008) strains and relation with integrons Curr Opin Biotechnol 19 260-265
  • [3] Sousa JC(2005)Antibiotics and antibiotic resistance in water environments J Antimicrob Chemother 56 962-964
  • [4] Peixe L(2005)Resistance among J Hazard Mater 122 195-204
  • [5] Baquero F(2004) to sulphonamides and other antimicrobials now little used in man Environ Sci Technol 38 3933-3940
  • [6] Martinez JL(2013)Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Hoje River in Sweden Environ Sci Pollut Res 20 8391-8403
  • [7] Canton R(2014)Photochemical fate of sulfa drugs in the aquatic environment: sulfa drugs containing five-membered heterocyclic groups Wetlands 34 1-13
  • [8] Bean DC(2012)Pharmaceutical residues in tidal surface sediments of three rivers in southeastern China at detectable and measurable levels Front Microbiol 3 106-123
  • [9] Livermore DM(2008)Occurrence and partitioning of antibiotics in the water column and bottom sediments from the intertidal zone in the Bohai Bay, China Science 320 100-103
  • [10] Papa I(2009)Increased levels of multiresistant bacteria and resistance genes after wastewater treatment and their dissemination into Lake Geneva, Switzerland Soil Biol Biochem 41 840-848
12345678910