Influence of Divalent Metal Ions on Biofilm Formation by Bacillus subtilis

被引：0
作者：
Т. L. Dinh
G. R. Akhmetova
D. S. Martykanova
N. L. Rudakova
М. R. Sharipova
机构：
[1] Kazan Federal University,Institute of Fundamental Medicine and Biology
[2] Volga Region state Academy of Physical Culture,undefined
[3] Sports and Tourism,undefined
来源：
BioNanoScience | 2019年 / 9卷
关键词：
Biofilms; Stress factors; Regulatory mutants; Metal ions; EDTA; DegU; CcpA;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The wild strain of B. subtilis 168, the protease-deficient strain of B. subtilis BRB14, and the regulatory mutants of B. subtilis 168 degU and B. subtilis 168 ccpA were examined for their ability to form biofilms under stress conditions—with elevated concentrations of divalent metal ions (Ca2+, Mg2+, Mn2+, and Zn2+), as well as in the presence of ethylenediaminetetraacetic acid (EDTA). It was shown that regulatory mutants are more resistant to the addition of divalent metal ions than wild and protease-deficient strains. At the same time, the introduction of EDTA reduces the level of biofilm formation by all strains on average by 50%.
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页码：521 / 527
页数：6
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  • [1] Pandit S(2017)Low concentrations of vitamin C reduce the synthesis of extracellular polymers and destabilize bacterial biofilms Frontiers in Microbiology 8 2599-18
  • [2] Ravikumar V(2008)Medical biofilms Biotechnology and Bioengineering 100 1-1450
  • [3] Abdel-Haleem AM(2014)Selected metal ions protect Bacillus subtilis biofilms from erosion Metallomics 6 1441-128
  • [4] Derouiche A(2016)Bacterial differentiation via gradual activation of global regulators Current Genetics 62 125-168
  • [5] Mokkapati VRSS(2013)Sticking together: building a biofilm the Bacillus subtilis way Nature Reviews. Microbiology 11 157-568
  • [6] Sihlbom C(2007)DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis Molecular Microbiology 65 554-409
  • [7] Mineta K(2007)Gradual activation of the response regulator DegU controls serial expression of genes for flagellum formation and biofilm formation in Bacillus subtilis Molecular Microbiology 66 395-1410
  • [8] Gojobori T(2008)SlrR/SlrA control the initiation of biofilm formation in Bacillus subtilis Molecular Microbiology 69 1399-27
  • [9] Gao X(2014)Phosphorylated DegU manipulates cell fate differentiation in the Bacillus subtilis biofilm Journal of Bacteriology 196 16-598
  • [10] Westerlund F(2014)Biofilm formation by Bacillus subtilis: new insights into regulatory strategies and assembly mechanisms Molecular Microbilogy 93 587-565
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