Alcohol Self-administration in Two Rat Lines Selectively Bred for Extremes in Anxiety-related Behavior

被引：0
作者：
Markus S H Henniger
Rainer Spanagel
Alexandra Wigger
Rainer Landgraf
Sabine M Hölter
机构：
[1] Max Planck Institute of Psychiatry,Department of Psychopharmacology
[2] Central Institute of Mental Health,undefined
[3] University of Heidelber,undefined
[4] J5,undefined
来源：
Neuropsychopharmacology | 2002年 / 26卷
关键词：
Emotionality; Voluntary ethanol self-administration; Anxiolysis; Tension reduction hypothesis;
D O I：
暂无
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学科分类号：
摘要：
According to the tension reduction hypothesis, individuals with an elevated anxiety level may be more sensitive to the anxiolytic effects of alcohol and may, therefore, have a higher predisposition to consume alcohol. To examine this hypothesis, we studied the drinking behavior as well as the sensitivity to the anxiolytic effect of alcohol in two rat lines that were bred and selected for differences in anxiety-related behavior on the elevated plus-maze: the extremely anxious HAB (high anxiety-related behavior) and the non-anxious LAB (low anxiety-related behavior) lines.
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页码：729 / 736
页数：7
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