Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes

被引:0
作者
Binbin Li
Zheng Wan
Guoliang Huang
Zunnan Huang
Xiangning Zhang
Dan Liao
Shengqun Luo
Zhiwei He
机构
[1] Guangdong Medical College,Department of Pathophysiology
[2] Dongguan,Key Laboratory for Medical Diagnostics of Guangdong Province
[3] Sino-American Cancer Research Institute,undefined
[4] Guangdong Medical College,undefined
来源
BMC Cancer | / 15卷
关键词
MSK1; NPC; EBV-LMP1; Transformation; Fra-1; c-Jun;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 280 条
[1]  
Chang ET(2006)The enigmatic epidemiology of nasopharyngeal carcinoma Cancer Epidemiol Biomarkers Prev 15 1765-77
[2]  
Adami HO(2014)Etiological factors of nasopharyngeal carcinoma Oral Oncol 50 330-8
[3]  
Tsao SW(2002)Epstein-Barr virus in the pathogenesis of NPC Semin Cancer Biol 12 431-41
[4]  
Yip YL(1993)Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1 Oncogene 8 1575-83
[5]  
Tsang CM(2001)LMP1 structure and signal transduction Semin Cancer Biol 11 435-44
[6]  
Pang PS(2009)The versatile role of MSKs in transcriptional regulation Trends Biochem Sci 34 311-8
[7]  
Lau VM(2002)MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts Mol Cell Biol 22 2871-81
[8]  
Zhang G(2003)Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1) EMBO J 22 1313-24
[9]  
Raab-Traub N(2001)MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells J Biol Chem 276 42534-42
[10]  
Hu LF(2003)MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14 EMBO J 22 2788-97