Suppressive effects of sivelestat on interleukin 8 and TNF-α production from LPS-stimulated granulocytes in whole blood culture

被引:0
作者
Shigehiro Shibata
Gaku Takahashi
Nobuki Shioya
Katsuya Inada
Shigeatsu Endo
机构
[1] Iwate Medical University,Department of Critical Care Medicine
来源
Journal of Anesthesia | 2010年 / 24卷
关键词
Sivelestat; Intracellular cytokine; Flow cytometry; Lipopolysaccharide;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:901 / 907
页数:6
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[1]  
Nakae H(1992)Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 20 864-74
[2]  
Endo S(1994)Significance of alpha-tocopherol and interleukin 8 in septic adult respiratory distress syndrome Res Commun Chem Pathol Pharmacol 84 197-202
[3]  
Inada K(1992)Two types of septic shock classified by the plasma levels of cytokines and endotoxin Circ Shock 38 264-274
[4]  
Kasai T(1993)Plasma tumor necrosis factor-α (TNF-α) levels in patients with burns Burns 19 124-127
[5]  
Yoshida M(1994)Platelet activating factor (PAF) acetyl hydrolase activity, type II phospholipase A2, and cytokine levels in patients with sepsis Res Commun Chem Pathol Pharmacol 83 289-295
[6]  
Endo S(1995)Plasma interleukin 8 and polymorphonuclear leukocyte elastase concentrations in patients with septic shock J Inflamm 45 136-142
[7]  
Inada K(1991)ONO-5046, a novel inhibitor of human neutrophil elastase Biochem Biophys Res Commun 177 814-820
[8]  
Inoue Y(1994)Mechanism for the increased permeability in endothelial monolayers induced by elastase Mediators Inflamm 3 11-16
[9]  
Kuwata Y(1994)Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep J Appl Physiol 77 1333-1340
[10]  
Suzuki M(2006)Sivelestat sodium hydrade improves septic acute lung injury by reducing alveolar dysfunction Res Commun Mol Pathol Pharmacol. 119 53-65