Therapy Insight: aortic aneurysm and dissection in Marfan's syndrome

被引：0
作者：
Francesco Ramirez
Harry C Dietz
机构：
[1] Chief Scientific Officer and Director of the Laboratory of Genetics and Organogenesis,the Victor A McKusick Professor of Department of Pediatrics, Medicine and Genetics, McKusick
[2] Hospital for Special Surgery,Nathans Institute of Genetic Medicine and Howard Hughes Medical Institute
[3] Johns Hopkins University,undefined
来源：
Nature Clinical Practice Cardiovascular Medicine | 2004年 / 1卷
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摘要：
In Marfan's syndrome, connective-tissue alterations promote aortic aneurysm and dissection. Despite advances in understanding the causes, treatments are still based on old protocols. The pathophysiology of aneurysm formation and progression is, however, being elucidated by new genetic data, discussed here, which might aid the advancement of therapy for Marfan-related aneurysm.
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页码：31 / 36
页数：5
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