Proton MR spectroscopy in neuroborreliosis: a preliminary study

被引：0
作者：
A. Ustymowicz
E. Tarasów
J. Zajkowska
J. Walecki
T. Hermanowska-Szpakowicz
机构：
[1] Medical Academy,Department of Radiology
[2] Medical Academy,Department of Infectious Diseases and Neuroinfections
来源：
Neuroradiology | 2004年 / 46卷
关键词：
Lyme disease; Magnetic resonance spectroscopy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report results of a magnetic resonance spectroscopy (MRS) study in 12 patients with neuroborreliosis. We used a PRESS sequence, placing an 8 cm3 voxel in normal-appearing white matter of the frontal lobe. Peaks indicating N-acetylaspartate (NAA), choline (Cho), creatine (Cr), myo-inositol (mI), lipids (Lip) and lactate (Lac) were identified and ratios of NAA/Cr, Cho/Cr, mI/Cr, Lip/Cr, Lac/Cr calculated. Significant increases in Cho/Cr and Lip/Cr were noted. No abnormality was found in mean NAA/Cr and Lac/Cr, but in four patients there was a decreased NAA peak; mI/Cr ratio was slightly increased. Although the spectroscopic profile in patients with neuroborreliosis seems to be nonspecific, MRS might be useful for assessing tissue damage of the central nervous system.
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页码：26 / 30
页数：4
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