Intracellular Compartmentalization of DNA Fragments in Cultured Airway Epithelial Cells Mediated by Cationic Lipids

被引：0
作者：
Adam R. Holmes
Austin F. Dohrman
Aaron R. Ellison
Kaarin K. Goncz
Dieter C. Gruenert
机构：
[1] Gene Therapy Core Center,Cardiovascular Research Institute, University of California
[2] F.I. Proctor Foundation,Departments of Laboratory Medicine and Stomatology
[3] University of California,undefined
[4] University of California,undefined
来源：
Pharmaceutical Research | 1999年 / 16卷
关键词：
gene therapy; human somatic cells; CFTR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The amount and intracellular distribution of DNA fragments (491 -bp) was characterized after transfection in vitro with a commercially available cationic lipid. Localization of fragment to the nucleus, its subcellular distribution, and integrity within the cells was determined for various times after transfection.
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页码：1020 / 1025
页数：5
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