A 47-year-old man with neuro-Sweet syndrome in association with Crohn's disease: A case report

被引：5

作者：

Hiari N. ^{[1
]}

Borland C. ^{[1
]}

机构：

[1] Hinchingbrooke Hospital, Huntingdon

来源：

Journal of Medical Case Reports | / 3卷 / 1期

关键词：

Skin Lesion; Bacterial Meningitis; Neutrophilic Infiltration; Aseptic Meningitis; Minor Criterion;

D O I：

10.4076/1752-1947-3-8997

中图分类号：

学科分类号：

摘要：

Introduction. Sweet's syndrome is a multi-system inflammatory disorder characterised by painful skin lesions and aseptic neutrophilic infiltration of various organs. We describe a case of Sweet's syndrome with aseptic meningitis in association with Crohn's disease (neuro-Sweet syndrome). This association has never been previously reported. Case presentation. A 47-year-old Caucasian male with known Crohn's disease presented with headache, fever and skin lesions resembling erythema nodosum. The cerebrospinal fluid revealed leukocyte pleocytosis and dominant neutrophils, but cultures were negative. A skin biopsy revealed neutrophilic dermatosis compatible with Sweet's disease. The patient made a prompt recovery without the use of corticosteroids. Conclusion. Because of its multisystem nature, Sweet's syndrome may present diagnostic difficulty to specialists. Correct diagnosis by skin biopsy will prompt appropriate treatment. © 2009 Hiari and Borland; licensee Cases Network Ltd.

引用

共 5 条

[1] Sweet R.D., An acute febrile neutrophilic dermatosis, Br J Dermatol, 76, pp. 349-356, (1964)
[2] Cohen P.R., Sweet's syndrome-a comprehensive review of an acute febrile neutrophilic dermatosis, Orphanet Journal of Rare Diseases, 2, (2007)
[3] Su W.P.D., Liu H.N.H., Diagnostic criteria for Sweet's syndrome, Cutis, 37, pp. 167-174, (1986)
[4] Von Der Driesch P., Sweet's (acute febrile neutrophilic dermatosis), J Am Acad Dermatol, 31, pp. 535-556, (1994)
[5] Hisanaga K., Hosokawa M., Sato N., Mochizuki H., Itoyama Y., Iwasaki Y., neuro-sweet Disease" benign recurrent encephalitis with neutrophilic dermatosis, Arch Neurol, 56, pp. 1010-1013, (1999)

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