Role of common fragile sites and corresponding genes in cancer development

[1] Dekaban A(1965)Persisting clone of cells with an abnormal chromosome in a woman previously irradiated J Nucl Med 6 740-746

[2] Glover TW(1984)DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes Hum Genet 67 136-142

[3] Berger C(2007)Chromosome fragile sites Annu Rev Genet 41 169-192

[4] Coyle J(2011)Hallmarks of cancer: the next generation Cell 144 646-674

[5] Echo B(2010)Genomic instability—an evolving hallmark of cancer Nat Rev Mol Cell Biol 11 220-228

[6] Durkin SG(2010)The landscape of somatic copy-number alteration across human cancers Nature 463 899-905

[7] Glover TW(2010)Signatures of mutation and selection in the cancer genome Nature 463 893-898

[8] Hanahan D(2005)DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Nature 434 864-870

[9] Weinberg RA(2005)Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Nature 434 907-913

[10] Negrini S(2011)Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress Mol Oncol 5 308-314

[1] Dekaban A(1965)Persisting clone of cells with an abnormal chromosome in a woman previously irradiated J Nucl Med 6 740-746

[2] Glover TW(1984)DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes Hum Genet 67 136-142

[3] Berger C(2007)Chromosome fragile sites Annu Rev Genet 41 169-192

[4] Coyle J(2011)Hallmarks of cancer: the next generation Cell 144 646-674

[5] Echo B(2010)Genomic instability—an evolving hallmark of cancer Nat Rev Mol Cell Biol 11 220-228

[6] Durkin SG(2010)The landscape of somatic copy-number alteration across human cancers Nature 463 899-905

[7] Glover TW(2010)Signatures of mutation and selection in the cancer genome Nature 463 893-898

[8] Hanahan D(2005)DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Nature 434 864-870

[9] Weinberg RA(2005)Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Nature 434 907-913

[10] Negrini S(2011)Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress Mol Oncol 5 308-314