Proton pump inhibitors in critically ill mechanically ventilated patients with COVID-19: protocol for a substudy of the Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

被引：0
作者：
Brittany B. Dennis
Lehana Thabane
Diane Heels-Ansdell
Joanna C. Dionne
Alexandra Binnie
Jennifer Tsang
Gordon Guyatt
Aijaz Ahmed
François Lauzier
Adam Deane
Yaseen Arabi
John Marshall
Nicole Zytaruk
Lois Saunders
Simon Finfer
John Myburgh
John Muscedere
Shane English
Marlies Ostermann
Miranda Hardie
Serena Knowles
Deborah Cook
机构：
[1] McMaster University,Department of Medicine
[2] McMaster University,Department of Health Research Methods, Evidence, and Impact
[3] Biostatistics Unit,Division of Critical Care
[4] St. Joseph’s Healthcare Hamilton,Departments of Medicine and Health Research Methods, Evidence, and Impact
[5] Research Institute,Department of Critical Care Medicine
[6] St. Joseph’s Healthcare Hamilton,Department of Gastroenterology and Hepatology
[7] McMaster University,Departments of Anesthesiology and Medicine and Critical Care Medicine
[8] McMaster University Health Sciences Center,Department of Critical Care Medicine
[9] Niagara Health System,Intensive Care Department
[10] Stanford University,Interdepartmental Division of Critical Care
[11] Université Laval,Critical Care Program
[12] University of Melbourne,Intensive Care Unit
[13] Melbourne Medical School,Department of Critical Care Medicine
[14] Ministry of the National Guard-Health Affairs,Department of Medicine
[15] King Saud Bin Abdulaziz University for Health Sciences,Clinical Epidemiology Program
[16] King Abdullah International Medical Research Center,Department of Critical Care
[17] University of Toronto,undefined
[18] The George Institute for Global Health,undefined
[19] Faculty of Medicine,undefined
[20] University of New South Wales,undefined
[21] St. George Hospital,undefined
[22] Queen’s University,undefined
[23] University of Ottawa,undefined
[24] Ottawa Hospital Research Institute,undefined
[25] King’s College London,undefined
来源：
Trials | / 24卷
关键词：
Randomization; Critically ill; COVID-19 pandemic; Hospital transfers; Stress ulceration; Gastrointestinal bleeding; Ventilator-associated pneumonia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 173 条
  • [1] Richardson S(2020)Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area JAMA 323 2052-1720
  • [2] Hirsch JS(2020)Clinical characteristics of coronavirus disease 2019 in China N Engl J Med 382 1708-1681
  • [3] Narasimhan M(2020)Association of inpatient use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 Circ Res 126 1671-2448
  • [4] Crawford JM(2020)Renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 N Engl J Med 382 2441-84
  • [5] McGinn T(2021)Effect of discontinuing vs continuing angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on days alive and out of the hospital in patients admitted with COVID-19 JAMA 325 254-1412
  • [6] Davidson KW(2021)Exploring drugs and vaccines associated with altered risks and severity of COVID-19: a UK Biobank cohort study of all ATC level-4 drug categories reveals repositioning opportunities Pharmaceutics 13 1514-845
  • [7] Barnaby DP(2021)Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching Gut 70 76-2516
  • [8] Becker LB(2022)Assessment of proton-pump inhibitor use, race, socioeconomic status, and mortality in individuals with COVID-19 Eur J Gastroenterol Hepatol 34 239-207
  • [9] Chelico JD(2020)Proton pump inhibitor use is associated with increased risk of severity and mortality from coronavirus disease 2019 (COVID-19) infection Dig Liver Dis 52 1410-797
  • [10] Cohen SL(2015)Prevalence and outcome of gastrointestinal bleeding and use of acid suppressants in acutely ill adult intensive care patients Intensive Care Med 41 833-381
12345678910