1H, 13C and 15N resonance assignment of the first N-terminal RNA recognition motif (RRM) of the human heterogeneous nuclear ribonucleoprotein H (hnRNP H)

被引:0
作者
Stéphanie Cabal
Carine van Heijenoort
Eric Guittet
机构
[1] ICSN-CNRS,Laboratoire de Chimie et Biologie Structurales
来源
Biomolecular NMR Assignments | 2007年 / 1卷
关键词
NMR resonance assignment; RNA recognition motif; Alternative splicing; Human immunodeficiency virus-1;
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学科分类号
摘要
Human heterogeneous nuclear ribonucleoprotein H (hnRNP H) regulates alternative splicing of HIV-1 Tat pre-mRNA. The structure of the first N-terminal domain (residues 1–104) of hnRNP H was solved and its binding to an exonic splicing silencer (pESS2) studied. For this, all backbone and 85% of side-chain resonance frequencies were assigned.
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页码:221 / 223
页数:2
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