Anaphylaxis to husband's seminal plasma and treatment by local desensitization

被引：19

作者：

Lee J. ^{[1
]}

Kim S. ^{[1
]}

Kim M. ^{[1
]}

Chung Y.-B. ^{[2
]}

Huh J.-S. ^{[3
]}

Park C. ^{[4
]}

Lee K.H. ^{[5
]}

Kim J. ^{[6
]}

机构：

[1] Department of Medicine, School of Medicine, Jeju National University, Jeju

[2] Department of Parasitology, School of Medicine, Jeju National University, Jeju

[3] Department of Urology, School of Medicine, Jeju National University, Jeju

[4] Department of OB and GYN, School of Medicine, Jeju National University, Jeju

[5] Department of Microbiology, School of Medicine, Jeju National University, Jeju

[6] Department of Otorhinolaryngology, School of Medicine, Jeju National University, Jeju

来源：

Clinical and Molecular Allergy | / 6卷 / 1期

关键词：

Skin Prick Test; Seminal Plasma; Extramarital Sexual Activity; Human Seminal Plasma; Repetitive Exposure;

D O I：

10.1186/1476-7961-6-13

中图分类号：

学科分类号：

摘要：

Hypersensitivity to human seminal fluid is rare but can We report a case of IgE-mediated anaphylaxis to plasma was diagnosed by skin prick tests and successfully treated by local desensitization. A 32-year-old woman suffering from angioedema and hypotension after exposure to semen was treated with epinephrine upon admission. Skin prick tests and immunoblotting for IgE binding components showed that she was sensitized to her husband's seminal plasma. Local desensitization, which persisted for six months, was achieved by intravaginal administration of serial dilutions of her husband's seminal plasma. © 2008 Lee et al; licensee BioMed Central Ltd.

引用

共 8 条

[1]

Tomitaka A., Suzuki K., Akamatsu H., Matsunaga K., Anaphylaxis to human seminal plasma, Allergy, 57, pp. 1081-1082, (2002)

[2]

Kim S.H., Jeon S.G., Park H.W., Kwon Y.E., Jeong Y.Y., Kim T.B., Park H.K., Kim S.S., Chang Y.S., Kim Y.K., Cho S.H., Min K.U., Kim Y.Y., A case of human seminal plasma allergy presenting as a severe generalized urticaria, Korean J Asthma Allergy Clin Immunol, 26, pp. 78-82, (2006)

[3]

Weidinger S., Ring J., Kohn F.M., IgE-medicated allergy against human seminal plasma, Chem Immunol Allergy, 88, pp. 128-138, (2005)

[4]

Park J.W., Ko S.H., Kim C.W., Bae S.W., Hong C.S., Seminal plasma anaphylaxis: Successful pregnancy after intravaginal desensitization and immunodetection of allergens, Allergy, 54, pp. 990-993, (1999)

[5]

Matfloff S.M., Local intravaginal desensitization to seminal fluid, J Allergy Clin Immunol, 91, pp. 1230-1231, (1993)

[6]

Shah A., Panjabi C., Human seminal plasma allergy: A review of rare phenomenon, Clin Exp Allergy, 34, pp. 827-838, (2004)

[7]

Shapiro S.S., Kooistra J.B., Schwartz D., Yunginger J.W., Haning R.V., Induction of pregnancy in a woman with seminal plasma allergy, Fertil Steril, 36, pp. 405-407, (1981)

[8]

De Cuyper C., Bogaerts Y., Vandekerckhove F., Gunst J., Intravaginal desensitization and successful pregnancy in a woman with seminal fluid allergy, J Allergy Clin Immunol, 97, pp. 1427-1428, (1996)

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