Enantio-, Regio-, and Chemoselective Reduction of Aromatic α-Diketones by Baker’s Yeast

被引：0

作者：

Nosrat O. Mahmoodi

Hussin G. Mohammadi

机构：

[1] Organic Research Laboratory,

[2] Department of Chemistry,undefined

[3] University of Guilan,undefined

[4] Rasht,undefined

[5] P.O. Box 1914,undefined

[6] Iran,undefined

来源：

Monatshefte für Chemie / Chemical Monthly | 2003年 / 134卷

关键词：

Keywords. Asymmetric synthesis; Chemoselectivity; Chiral α-hydroxy ketones; α-Diketone; Yeast.;

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摘要：

The enantio- and regioselective reduction of several symmetric and nonsymmetrically para-substituted benzil derivatives (21–92%) was achieved by means of Saccharomyces cerevisiae (baker’s yeast). After modification of the reaction conditions reduction of nonsymmetric α-diketones led chemoselectively to chiral α-hydroxy ketones with up to 82% ee.

引用

页码：1283 / 1288

页数：5