Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

被引:0
|
作者
Xiao-Dan Mo
Li-Ping Gao
Qing-Jun Wang
Jie Yin
Yu-Hong Jing
机构
[1] Lanzhou University,Institute of Anatomy and Histology & Embryology, Neuroscience, School of Basic Medical Sciences
[2] Lanzhou University,Key Laboratory of Preclinical Study for New Drugs of Gansu province
[3] Lanzhou University,Institute of Biochemistry and Molecular Biology, School of Basic Medical Sciences
关键词
IAPP; Lipid; Pancreatic islet; T2DM; Insulin; Palmitate;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Unaltered pancreatic islet blood perfusion in islet amyloid polypeptide-deficient mice
    Carlsson, PO
    Karlsson, E
    Mulder, H
    Gebre-Medhin, S
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2002, 146 (01) : 107 - 112
  • [22] Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells
    Lukinius, A
    Korsgren, O
    Grimelius, L
    Wilander, E
    ENDOCRINOLOGY, 1996, 137 (12) : 5319 - 5325
  • [23] Fibril growth captured by electrical properties of amyloid-β and human islet amyloid polypeptide
    Awasthi, Prasoon
    Singh, Anurag
    Khatun, Suparna
    Gupta, Amar Nath
    Das, Soumen
    PHYSICAL REVIEW E, 2020, 101 (06)
  • [24] Insulin and islet amyloid polypeptide 'amylin' form stable molecular complexes in vitro affecting fibril formation
    Clark, A
    Jaikaran, ETAS
    Tito, P
    Robinson, CV
    Fraser, PE
    DIABETOLOGIA, 1999, 42 : A145 - A145
  • [25] B cell granule peptides affect human islet amyloid polypeptide (IAPP) fibril formation in vitro
    Janciauskiene, S
    Eriksson, S
    Carlemalm, E
    Ahren, B
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 236 (03) : 580 - 585
  • [26] Aromatic interactions are not required for amyloid fibril formation by islet amyloid polypeptide but do influence the rate of fibril formation and fibril morphology
    Marek, Peter
    Abedini, Andisheh
    Song, BenBen
    Kanungo, Mandakini
    Johnson, Megan E.
    Gupta, Ruchi
    Zaman, Warda
    Wong, Stanislaus S.
    Raleigh, Daniel P.
    BIOCHEMISTRY, 2007, 46 (11) : 3255 - 3261
  • [27] Effect of Lipid Type on the Binding of Lipid Vesicles to Islet Amyloid Polypeptide Amyloid Fibrils
    Sasahara, Kenji
    Hall, Damien
    Hamada, Daizo
    BIOCHEMISTRY, 2010, 49 (14) : 3040 - 3048
  • [28] Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol
    Mishra, Rajesh
    Sellin, Daniel
    Radovan, Diana
    Gohlke, Andrea
    Winter, Roland
    CHEMBIOCHEM, 2009, 10 (03) : 445 - +
  • [29] Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro
    Kayed, R
    Bernhagen, J
    Greenfield, N
    Sweimeh, K
    Brunner, H
    Voelter, W
    Kapurniotu, A
    JOURNAL OF MOLECULAR BIOLOGY, 1999, 287 (04) : 781 - 796
  • [30] Influence of methionine–ruthenium complex on the fibril formation of human islet amyloid polypeptide
    Gehui Gong
    Jufei Xu
    Xiangyi Huang
    Weihong Du
    JBIC Journal of Biological Inorganic Chemistry, 2019, 24 : 179 - 189