Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

被引:0
|
作者
Xiao-Dan Mo
Li-Ping Gao
Qing-Jun Wang
Jie Yin
Yu-Hong Jing
机构
[1] Lanzhou University,Institute of Anatomy and Histology & Embryology, Neuroscience, School of Basic Medical Sciences
[2] Lanzhou University,Key Laboratory of Preclinical Study for New Drugs of Gansu province
[3] Lanzhou University,Institute of Biochemistry and Molecular Biology, School of Basic Medical Sciences
关键词
IAPP; Lipid; Pancreatic islet; T2DM; Insulin; Palmitate;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [11] ISLET AMYLOID POLYPEPTIDE, ISLET AMYLOID, AND DIABETES MELLITUS
    Westermark, Per
    Andersson, Arne
    Westermark, Gunilla T.
    PHYSIOLOGICAL REVIEWS, 2011, 91 (03) : 795 - 826
  • [12] ISLET AMYLOID POLYPEPTIDE (IAPP) AND PANCREATIC-ISLET AMYLOID DEPOSITION IN DIABETIC AND NONDIABETIC PATIENTS
    NARITA, R
    TOSHIMORI, H
    NAKAZATO, M
    KURIBAYASHI, T
    TOSHIMORI, T
    KAWABATA, K
    TAKAHASHI, K
    MASUKURA, S
    DIABETES RESEARCH AND CLINICAL PRACTICE, 1992, 15 (01) : 3 - 14
  • [13] ISLET AMYLOID POLYPEPTIDE
    WESTERMARK, P
    WILANDER, E
    JOHNSON, KH
    LANCET, 1987, 2 (8559): : 623 - 623
  • [14] Evidence for islet amyloid fibril formation in a new mouse model of insulinoma producing and secreting human islet amyloid polypeptide
    Andrikopoulos, S
    Verchere, CB
    Howell, WM
    Wight, TN
    Kahn, SE
    DIABETES, 1998, 47 : A197 - A197
  • [15] Small-molecule inhibitors of islet amyloid polypeptide fibril formation
    Mishra, Rajesh
    Bulic, Bruno
    Sellin, Daniel
    Jha, Suman
    Waldmann, Herbert
    Winter, Roland
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (25) : 4679 - 4682
  • [16] Islet amyloid polypeptide does not suppress pancreatic cancer
    Taylor, Austin J.
    Panzhinskiy, Evgeniy
    Orban, Paul C.
    Lynn, Francis C.
    Schaeffer, David F.
    Johnson, James D.
    Kopp, Janel L.
    Verchere, C. Bruce
    MOLECULAR METABOLISM, 2023, 68
  • [17] Inhibition of islet amyloid polypeptide fibril formation by natural polyphenols.
    Abioye, Raliat
    Udenigwe, Chibuike
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2021, 98 : 193 - 194
  • [18] Lipid membranes modulate the structure of islet amyloid polypeptide
    Jayasinghe, SA
    Langen, R
    BIOCHEMISTRY, 2005, 44 (36) : 12113 - 12119
  • [19] In Vitro Interactions Between Amyloid Beta and Islet Amyloid Polypeptide
    Vandiver, Leah
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 56A - 56A
  • [20] How Islet Amyloid Polypeptide Damages Lipid Bilayers
    Lee, Chang-Chun
    Sun, Yen
    Huang, Huey W.
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 616A - 616A