The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles

被引:0
作者
Bernd H. Zinselmeyer
Anthony N. Vomund
Brian T. Saunders
Michael W. Johnson
Javier A. Carrero
Emil R. Unanue
机构
[1] Washington University School of Medicine,Department of Pathology and Immunology, Division of Immunobiology
[2] BJC Institute of Health,undefined
来源
Diabetologia | 2018年 / 61卷
关键词
Beta cells; Fluorescence microscopy; Islet; Islet autoimmunity; Macrophage;
D O I
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学科分类号
摘要
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页码:1374 / 1383
页数:9
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  • [1] Calderon B(2012)Antigen presentation events in autoimmune diabetes Curr Opin Immunol 24 119-128
  • [2] Unanue ER(1979)Prolongation of islet allograft survival following in vitro culture (24 Science 204 312-313
  • [3] Lacy PE(1980)C) and a single injection of ALS Aust J Exp Biol Med Sci 58 441-447
  • [4] Davie JM(2015)Reversal of diabetes by allogenic islet transplantation without immunosuppression J Exp Med 212 1497-1512
  • [5] Finke EH(2014)The pancreas anatomy conditions the origin and properties of resident macrophages Immunity 41 657-669
  • [6] Bowen KM(2014)A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes Diabetes 63 1698-1711
  • [7] Lafferty KJ(2017)Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction J Exp Med 214 2369-2385
  • [8] Calderon B(2016)The islet-resident macrophage is in an inflammatory state and senses microbial products in blood Nat Immunol 17 34-40
  • [9] Carrero JA(2016)New insights into the multidimensional concept of macrophage ontogeny, activation and function Nat Immunol 17 2-8
  • [10] Ferris ST(2014)The development and maintenance of resident macrophages Cell 159 1312-1326