Antimicrobial resistance among commensal isolates of Escherichia coli and Staphylococcus aureus in the Indonesian population inside and outside hospitals

被引:0
作者
E. S. Lestari
J. A. Severin
P. M. G. Filius
K. Kuntaman
D. O. Duerink
U. Hadi
H. Wahjono
H. A. Verbrugh
机构
[1] Diponegoro University,Department of Clinical Microbiology, Dr. Kariadi Hospital
[2] Erasmus MC, School of Medicine
[3] University Medical Center Rotterdam,Department of Medical Microbiology and Infectious Diseases
[4] Airlangga University,Department of Clinical Microbiology, Dr. Soetomo Hospital
[5] Leiden University Medical Center, School of Medicine
[6] Airlangga University,Department of Infectious Diseases
来源
European Journal of Clinical Microbiology & Infectious Diseases | 2008年 / 27卷
关键词
Antimicrobial Resistance; Resistance Rate; Primary Health Center; mecA Gene; Nasal Carriage;
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摘要
The prevalence of antimicrobial resistance among the commensal microflora was examined in the Indonesian population inside and outside hospitals. A total of 3,995 individuals were screened in two major urban centers. Among Escherichia coli from rectal samples (n = 3,284) the prevalence of resistance to ciprofloxacin and other classes of antibiotics was remarkably high, especially in individuals at the time of discharge from hospital. Staphylococcus aureus isolates (n = 361) were often resistant to tetracycline (24.9%), but this was not associated with hospital stay. Two S. aureus isolates harbored the mecA gene. Regional differences in resistance rates exist, suggesting regional differences in selection pressure, i.e., antibiotic usage patterns. The results show that antimicrobial resistance among commensal E. coli and S. aureus has emerged in Indonesia.
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