Chrysin mitigates diclofenac-induced hepatotoxicity by modulating oxidative stress, apoptosis, autophagy and endoplasmic reticulum stress in rats

[1] Buer JK(2014)Origins and impact of the term ‘NSAID’ Inflammopharmacology 22 263-267

[2] Sathishkumar P(2021)Hazardous impact of diclofenac on mammalian system: Mitigation strategy through green remediation approach J Hazard Mater 419 126135-95

[3] Mohan K(2022)Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER Sci Rep 12 2631-51

[4] Meena RAA(2022)6-Paradol alleviates Diclofenac-induced acute kidney injury via autophagy enhancement-mediated by AMPK/AKT/mTOR and NLRP3 inflammasome pathways Environ Toxicol Pharmacol 91 103817-1514

[5] Imai T(2016)High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study BMC Nephrol 17 189-137

[6] Hazama K(2018)Diclofenac – induced hepatotoxicity: Low dose of omega-3 fatty acids have more protective effects Toxicol Rep 5 90-654

[7] Kosuge Y(2018)Diclofenac-induced renal toxicity in female Wistar albino rats is protected by the pre-treatment of aqueous leaves extract of Madhuca longifolia through suppression of inflammation, oxidative stress and cytokine formation Biomed Pharmacother 98 45-208

[8] Suzuki S(2020)Kolaviron diminishes diclofenac-induced liver and kidney toxicity in wistar rats via suppressing inflammatory events, upregulating antioxidant defenses, and improving hematological indices Dose-Response 18 1559325819899256-337

[9] Ootsuka S(2021)Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach Biol Trace Elem Res 199 1501-500

[10] El-Maadawy WH(2020)Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis Neurotoxicology 76 126-958

[1] Buer JK(2014)Origins and impact of the term ‘NSAID’ Inflammopharmacology 22 263-267

[2] Sathishkumar P(2021)Hazardous impact of diclofenac on mammalian system: Mitigation strategy through green remediation approach J Hazard Mater 419 126135-95

[3] Mohan K(2022)Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER Sci Rep 12 2631-51

[4] Meena RAA(2022)6-Paradol alleviates Diclofenac-induced acute kidney injury via autophagy enhancement-mediated by AMPK/AKT/mTOR and NLRP3 inflammasome pathways Environ Toxicol Pharmacol 91 103817-1514

[5] Imai T(2016)High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study BMC Nephrol 17 189-137

[6] Hazama K(2018)Diclofenac – induced hepatotoxicity: Low dose of omega-3 fatty acids have more protective effects Toxicol Rep 5 90-654

[7] Kosuge Y(2018)Diclofenac-induced renal toxicity in female Wistar albino rats is protected by the pre-treatment of aqueous leaves extract of Madhuca longifolia through suppression of inflammation, oxidative stress and cytokine formation Biomed Pharmacother 98 45-208

[8] Suzuki S(2020)Kolaviron diminishes diclofenac-induced liver and kidney toxicity in wistar rats via suppressing inflammatory events, upregulating antioxidant defenses, and improving hematological indices Dose-Response 18 1559325819899256-337

[9] Ootsuka S(2021)Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach Biol Trace Elem Res 199 1501-500

[10] El-Maadawy WH(2020)Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis Neurotoxicology 76 126-958