Free Radical Processes in the Liver of Adult and Old Rats during Stress

被引：0
|
作者：
V. V. Davydov
I. V. Zakharchenko
V. G. Ovsyannikov
机构：
[1] Academy of Medical Sciences,Laboratory of Age
[2] Rostov State Medical University,Specific Endocrinology and Metabolism, Institute for Child and Adolescent Welfare
来源：
Bulletin of Experimental Biology and Medicine | 2004年 / 137卷
关键词：
oxidative stress; immobilization; aging; liver;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We measured the content of free radical lipid peroxidation products, intensity of induced lipid peroxidation, and concentration of carbonylated proteins in the liver of adult (10-12 months) and old rats (22-25 months) subjected to 30-min immobilization. Changes in the intensity of induced lipid peroxidation in homogenates and accumulation of carbonylated proteins in subcellular liver fractions indicate that immobilization stimulates free radical generation in the liver of both adult and old rats. The intensity of this process in old rats surpassed that in adult animals.
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页码：139 / 142
页数：3
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