Intestinal microbiome-gut-brain axis and irritable bowel syndrome; [Intestinale Mikrobiom-Darm-Hirn-Achse und Reizdarmsyndrom]

被引：66
作者：
Moser G. [1 ]
Fournier C. [1 ]
Peter J. [1 ]
机构：
[1] Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, Vienna
来源：
Wiener Medizinische Wochenschrift | 2018年 / 168卷 / 3-4期
关键词：
Anxiety; Depression; Enterotype; Psyche; Stress;
D O I：
10.1007/s10354-017-0592-0
中图分类号：
学科分类号：
摘要：
Psychological comorbidity is highly present in irritable bowel syndrome (IBS). Recent research points to a role of intestinal microbiota in visceral hypersensitivity, anxiety, and depression. Increased disease reactivity to psychological stress has been described too. A few clinical studies have attempted to identify features of dysbiosis in IBS. While animal studies revealed strong associations between stress and gut microbiota, studies in humans are rare. This review covers the most important studies on intestinal microbial correlates of psychological and clinical features in IBS, including stress, anxiety, and depression. © 2017, The Author(s).
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页码：62 / 66
页数：4
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