Expression of the Aspergillus nidulans xlnC gene encoding the X34 endo-xylanase is subject to carbon catabolite repression and pH control

被引：0
作者：
A.P. MacCabe
D. Ramón
机构：
[1] Instituto de Agroquímica y Tecnología de Alimentos,Departamento de Biotecnología
[2] Consejo Superior de Investigaciones Científicas,undefined
来源：
World Journal of Microbiology and Biotechnology | 2001年 / 17卷
关键词：
carbon catabolite repression; CreA; pH regulation; xylanase X;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Expression of the Aspergillus nidulans xylanase gene xlnC is subject to regulation by carbon catabolite repression and ambient pH. In the presence of glucose, xlnC transcription is repressed by the zinc finger transcription factor CreA. These data have been confirmed using the extremely derepressed mutant creAd30. Expression of xlnC is elevated at alkaline ambient pH and also in alkalinity-mimicking A. nidulans mutants.
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页码：57 / 60
页数：3
相关论文
共 89 条
[1]  
Arst H.N.(1990)An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression Molecular Microbiology 4 851-854
[2]  
Tollervey D.(1994)Two new genes involved in signalling ambient pH in Aspergillus nidulans Molecular and General Genetics 245 787-790
[3]  
Dowzer C.E.A.(1986)Regulation of gene expression by pH of the growth medium in Aspergillus nidulans Molecular and General Genetics 203 346-353
[4]  
Kelly J.M.(1994)Two different, adjacent and divergent zinc finger binding sites are necessary for CreA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans EMBO Journal 13 407-415
[5]  
Arst H.N.(1991)Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans Molecular and Cellular Biology 11 5701-dy5709
[6]  
Bignell E.(1996)Three binding sites for the Aspergillus nidulans PacC zinc-finger transcription factor are necessary and sufficient for regulation by ambient pH of the isopenicillin N synthase gene promoter Journal of Biological Chemistry 271 28,825-28,830
[7]  
Tilburn J.(1992)Xylanase production by Aspergillus nidulans FEMS Microbiology Letters 91 91-96
[8]  
Caddick M.X.(1993)Specific binding sites in the alcR and alcA promoters of the ethanol regulon for the CreA suppressor mediating carbon catabolite repression in Aspergillus nidulans Molecular Microbiology 7 847-857
[9]  
Brownlee A.G.(1996)Purification and regulation of the synthesis of a b-xylosidase from Aspergillus nidulans FEMS Microbiology Letters 135 287-293
[10]  
Arst H.N.(1996)Identification, isolation and sequence of the Aspergillus nidulans xlnC gene encoding the 34-kDa xylanase Gene 175 29-33
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