Nitric oxide in preterm infant with pulmonary hypoplasia

被引：14

作者：

Kabra N.S. ^{[1
,2
]}

Kluckow M.R. ^{[1
]}

Powell J. ^{[1
]}

机构：

[1] Department of Neonatology, University of Sydney, Royal North Shore Hospital, St Leonards

[2] Apt. 310, Hamilton, Ont. L8S 2H 6

来源：

The Indian Journal of Pediatrics | 2004年 / 71卷 / 5期

关键词：

Inhaled nitric oxide; Premature infant; Pulmonary hypoplasia;

D O I：

10.1007/BF02725633

中图分类号：

学科分类号：

摘要：

Premature infants with hypoplastic lungs may have elevated pulmonary vascular resistance with right to left shunt across ductus arteriosus and/or foramen ovale. Inhaled nitric oxide (NO) being selective pulmonary vasodilator without significant effects on systemic circulation can potentially reverse this shunt. The authors herewith report a case of a premature infant with severe hypoxemic respiratory failure after preterm premature prolonged rupture of membranes leading to oligohydramnios and pulmonary hypoplasia that was treated successfully with NO and describe the neurodevelopmental outcome at 1 year of age.

引用

页码：427 / 429

页数：2

共 7 条

[1]

Finer N.N., Barrington K.J., Nitric oxide for respiratory failure in infants born at or near term, Cochrane Database Syst Rev, 4, (2001)

[2]

Barrington K.J., Finer N.N., Inhaled nitric oxide for respiratory failure in preterm infants, Cochrane Database Syst Rev, 4, (2001)

[3]

Geary C., Whitsett J., Inhaled nitric oxide for oligohydramnios-induced pulmonary hypoplasia: A report of two cases and review of the literature, J Perinatol, 22, pp. 82-85, (2002)

[4]

Peliowski A., Finer N.N., Etches P.C., Tierney A.J., Ryan C.A., Inhaled nitric oxide for premature infants after prolonged rupture of the membranes, J Pediatr, 126, pp. 450-453, (1995)

[5]

Bhutani V.K., Abbasi S., Weiner S., Neonatal pulmonary manifestations due to prolonged amniotic leak, Am J Perinatol, 3, pp. 225-230, (1986)

[6]

Kilbride H.W., Yeast J.D., Thibeault D.W., Intrapartum and delivery room management of premature rupture of membranes complicated by oligohydramnios, Clin Perinatol, 16, pp. 863-888, (1989)

[7]

Winn H.N., Chen M., Amon E., Leet T.L., Shumway J.B., Mostello D., Neonatal pulmonary hypoplasia and perinatal mortality in patients with midtrimester rupture of amniotic membranes-a critical analysis, Am J Obstet Gynecol, 182, pp. 1638-1644, (2000)

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