The Effect of Dried Beancurd on Bone Mineral Density in Postmenopausal Chinese Women: A 2-Year Randomized Controlled Trial

被引：0
作者：
Lei Li
Meijun Sun
Jianping Sun
Hangru Kong
Wenwen Zhong
Hong Wang
机构：
[1] Xiamen University,State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Public Health School
[2] Qingdao Center for Disease Control and Prevention,undefined
[3] General Hospital of People’s Liberation Army,undefined
来源：
Calcified Tissue International | 2019年 / 105卷
关键词：
Dried beancurd; Postmenopausal women; BMD; Calcium; Isoflavones;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Soy foods contain several components such as isoflavones, calcium and protein that potentially modulate bone turnover and increase bone mineral density (BMD) in postmenopausal women. The study is to evaluate the effect of dried beancurd supplementation on skeletal health in postmenopausal Chinese women. Three hundred postmenopausal women aged 50–65 years were assigned into two groups, receiving 100 g dried beancurd or rice cake a day for 2 years. BMD at the lumbar spine and right proximal femur were measured with a dual-energy X-ray absorptiometry. The bone turnover biomarkers of serum alkaline phosphatase (ALP), bone Gla protein (BGP) and urinary N-telopeptide cross-links of collagen normalized for creatinine (NTX/CRT) were also determined. Serum isoflavone concentration was analyzed by high performance liquid chromatography. The 2-year dried beancurd supplementation generated a significant increase in lumbar spine BMD. An obvious decrease was found in urinary NTX/CRT, and a significant increase was detected in serum isoflavone concentration. The dried beancurd supplementation had no effect on changes of right proximal femur BMD and concentrations of serum ALP and BGP. Daily supplementation of dried beancurd could increase BMD of lumbar spine, but does not slow bone loss at right proximal femur in postmenopausal Chinese women.
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页码：573 / 581
页数：8
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