TNF antagonists opened the way to personalized medicine in rheumatoid arthritis

被引：4
作者：
Breedveld F. [1 ]
机构：
[1] Leiden University Medical Center, Leiden
来源：
Molecular Medicine | 2014年 / 20卷 / Suppl 1期
关键词：
Rheumatoid Arthritis (RA); Autoinflammatory Diseases; Synovial Lining; BeST Study; Dynamic Treatment Strategies;
D O I：
10.2119/molmed.2014.00168
中图分类号：
学科分类号：
摘要：
Rheumatoid arthritis (RA) is an autoimmune disease resulting from a largely unknown interaction between genetically determined and environmental factors. Progress in the understanding of this chronic inflammation in the synovial lining of joints has led to the insight that one cytokine, tumor necrosis factor (TNF), has an important role. This insight started the development of a series of targeted and highly effective therapeutics for RA and a range of other autoinflammatory diseases. RA has changed from a severely debilitating disease into a disease where progression can be stopped in most of the patients. © 2014 Molecular Medicine All rights received.
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页码：S7 / S9
页数：2
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