The role of TLC in the screening of inherited metabolic diseases

被引：0
|
作者：
E. Marklová
机构：
[1] Charles University,Department of Pediatrics, Laboratory of Inherited Metabolic Diseases, Faculty of Medicine and Faculty Hospital
来源：
Chromatographia | 1997年 / 45卷
关键词：
Thin-layer chromatography; Screening; Inherited metabolic diseases;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Thin-layer chromatography (TLC) is a rapid, reliable and inexpensive screening technique for diagnosis of inherited metabolic diseases (IMD). Our screening program encompasses five main situations where the use of TLC is considered to be vindicated: (i) analysis of amino acids; (ii) screening for sugar defects; (iii) detection of pathological oligosaccharidurias; (iv) screening for organic acid disorders; and (v) detection of abnormalities in tryptophan metabolism. Examples are presented of chromatograms obtained from pathological samples.
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页码：195 / 198
页数：3
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