Rational multidrug therapy in the treatment of neuropathic pain

被引：60
作者：
Backonja M.-M. [1 ]
Irving G. [1 ]
Argoff C. [1 ]
机构：
[1] Department of Neurology, University of Wisconsin-Madison, Madison, WI 53792
来源：
Current Pain and Headache Reports | 2006年 / 10卷 / 1期
关键词：
Neuropathic Pain; Gabapentin; Venlafaxine; Pregabalin; Oxycodone;
D O I：
10.1007/s11916-006-0007-1
中图分类号：
学科分类号：
摘要：
Multidrug therapy (MDT) has been widely accepted and used as a standard of practice in most areas of medical practice, including neuropathic pain. Because neuropathic pain is a new field of medical science and practice, standards for its treatment including MDT are still evolving. In this article, we present rationale and principals for the MDT of neuropathic pain based on our best understandings of the underlying mechanisms of the disease processes and the actions of drugs, the goal being to maximize benefits and minimize adverse effects. MDT for neuropathic pain is based on a comprehensive clinical neuropathic pain assessment and ongoing monitoring of the drug therapy's efficacy and adverse effects, administering one drug at the time. Copyright © 2006 by Current Science Inc.
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页码：34 / 38
页数：4
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