Diagnostic criteria of latent autoimmune diabetes in adults (LADA): A review and reflection

被引：20
作者：
Liao Y. [1 ]
Xiang Y. [1 ]
Zhou Z. [1 ]
机构：
[1] Diabetes Center, 2nd Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University
来源：
Frontiers of Medicine | 2012年 / 6卷 / 3期
基金：
中国国家自然科学基金;
关键词：
age of diagnosis; autoantibodies; diagnostic criteria; insulin independence; LADA;
D O I：
10.1007/s11684-012-0201-y
中图分类号：
学科分类号：
摘要：
Diabetes has become a major public health problem in China nowadays. There are almost 97 million diabetic patients nationwide. Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes. Although it has been reported for about 20 years, the diagnostic criteria of this disease remain controversial. The discussion mainly focused on serum autoantibodies, period of insulin need and age of diagnosis. Besides, β cell function, metabolic parameters, genetic factors and cell immunity may also contribute to the formulation of the criteria. Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults. © 2012 Higher Education Press and Springer-Verlag Berlin Heidelberg.
引用
收藏
页码：243 / 247
页数：4
相关论文
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